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Diagnostic culture-independent methods in lieu of evaluation using stool culture should be used in situations where the individual patient is at high risk of spreading disease to others and during known or suspected outbreaks.
Culture-independent methods for stool diagnostics should be used in cases of dysentery, moderate-severe disease, and symptoms lasting >7 days to clarify the etiology of the patient’s illness and enable specifically directed therapy.
Traditional methods of diagnosis (bacterial culture, microscopy with and without special stains and immunofluorescence, and antigen testing) fail to reveal the etiology of the majority of cases of acute diarrheal infection. Culture-independent methods of diagnosis should be recommended in lieu of or as an adjunct to traditional methods.

Antibiotics prevent millions of deaths each year and remain the primary treatment for potentially fatal bacterial infections. Yet inappropriate prescription rates and overuse have led to antibiotic resistance that has created a global health emergency and kills at least 700,000 people a year. If no action is taken, it is predicted to increase to 10 million deaths per year by 2050¹.
It has been estimated that by 2050, 10 million worldwide deaths could result from antibiotic resistance, making it deadlier than cancer².

sean@rizco.com2022-12-02T15:58:47+00:00December 2, 2022|

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genesislabs222022-11-18T14:40:41+00:00November 17, 2022|

New report calls for urgent action to avert antimicrobial resistance crisis [Internet]. World Health Organization. World Health Organization; 2019 [cited 2021Mar30]. Available here.
Review on antimicrobial resistance. Tackling drug-resistant infections globally: Final report and recommendations [Internet]. London (UK). 2006 May. [cited 2020 Dec 11]. Available here.
Karzai W, Oberhoffer M, Meier-Hellmann A, Reinhart K. Procalcitonin—a new indicator of the systemic response to severe infections. Infection. 1997 Nov 1;25(6):329-34.